| The Salk Institute for Biological Studies and Burnham | | | | Young, Ph.D. at Salk, combined several layers of |
| Institute for Medical Research today announced 295 | | | | genome-wide analysis to identify cellular proteins that |
| host cell factors that are involved in human | | | | aid the virus in establishing an infection. |
| immunodeficiency virus (HIV) infection. The study, | | | | "HIV has just nine genes, coding for 15 proteins, |
| published in the Oct. 3 issue of Cell, could lead to the | | | | compared to bacteria, which harbour several |
| development of a new class of HIV therapeutics | | | | thousand genes, or humans, with over 20,000 |
| aimed at disrupting the human-HIVhuman-HIV | | | | genes," said Chanda, associate professor in the |
| interactions that lead to viral infection. | | | | Infectious & Inflammatory Disease Center at |
| The research, a collaborative effort between the | | | | Burnham and an adjunct faculty member at Salk. "We |
| laboratories of Sumit K. Chanda, Ph.D, previously at | | | | have known for a long time that HIV hijacks our |
| the Genomics Institute of the Novartis Research | | | | cellular proteins to complete its life cycle. This study |
| Foundation (GNF) and now at Burnham and John | | | | now lays out its flight plan. |