What Causes Rheumatoid Arthritis?

The self-destructive immune response of rheumatoidexamination. An x ray, a blood test for rheumatoid
arthritis may be caused by a combination of geneticfactor, and other laboratory tests also may help your
susceptibility and an environmental trigger. Changingdoctor to distinguish between other conditions and
hormones also may play an important part in therheumatoid arthritis.
disease, possibly in response to an infection from theWhen to See a Doctor
environment.As we get older, many of us will feel occasional joint
More than one gene has been linked to risk forpain or discomfort that comes and goes. This does
rheumatoid arthritis. Specific genes may increase anot usually require professional treatment. But you
person's chance of developing the disease, and alsoshould see a doctor if:
could partially determine how serious his or her• you regularly have morning stiffness in your
condition is. However, since not all people with ajoints
genetic predisposition to rheumatoid arthritis actually• you experience persistent joint pain that does
have the disease, other factors must be important.not improve with self-care
A specific environmental trigger has not yet been• the joint pain is increasing
found, but some research suggests that infection by• the joint is swollen, red, hot, or tender to the
a virus or bacterium leads to rheumatoid arthritis intouch
genetically susceptible people. This does not mean• it is difficult to move without pain
that rheumatoid arthritis is contagious. People with• you also have a fever
rheumatoid arthritis appear to have more antibodies• several joints on the left and right sides of your
in the synovial fluid in their joints, suggesting thatbody are affected
there may be an infection.What to Expect During the Exam
Low levels of hormones from the adrenal gland areThere are many sources of joint pain, and in early
common in people with rheumatoid arthritis, but howrheumatoid arthritis it is often difficult to rule out
hormones interact with environmental and geneticother causes of your symptoms. Your doctor will try
factors is unknown. Hormone changes may contributeto determine the causes of your symptoms based
to the progression of the rheumatoid arthritis.on your description, your medical history, and a
Conditions That Can Cause Rheumatoid Arthritisphysical examination. They also may use x rays and
Rheumatoid arthritis can occur independently fromlaboratory tests to distinguish between other
other conditions, but its causes and relationship toconditions and rheumatoid arthritis.
other diseases are not well understood. A differentA blood test can be done for rheumatoid factor,
form of chronic arthritis can sometimes develop intowhich is present in 80% of people with rheumatoid
rheumatoid arthritis. It also is possible that infectionsarthritis, but it may not be visible early on. In addition,
or other environmental triggers exist that can causenot everyone with rheumatoid factor has arthritis.
rheumatoid arthritis in people that already have aThe initial exam is also important in monitoring
gene for the disease.changes in your health over time. If rheumatoid
Diagnosing Rheumatoid Arthritisarthritis is diagnosed, regular doctor visits will allow
It often is difficult to rule out alternate causes ofyou to adjust treatments as needed.
joint pain during the early stages of rheumatoidTo learn about button phobia and cat phobia, visit the
arthritis. A diagnosis is based on the symptoms you10 Most Common Phobias website.
describe, your medical history, and a physical