Aciclovir Could Slow Hiv Progress

After disappointing news that the herpes medicationof the virus progressing by 16%. For those taking
aciclovir does not prevent the transmission of theacivlovir 284 saw their CD4 count fall below 200, the
HIV virus as previously hoped, there has been moresign that the virus is getting worse, compared to 324
positive results from a study into whether the samein the placebo group.
medication could slow down the progression of theThey also discovered that for those whose immune
virus.systems were relatively healthy, the medication
Published in the Lancet, the research showed thatreduced the chance of their CD4 count talking below
though modest, aciclovir can slow down the progress350 cells per microlitre by 19%.
of HIV, increasing time before it develops intoWhile the medication is nowhere near as effective at
full-blown AIDS.suppressive the HIV virus as the recommended
The research team recruited volunteers to take partcourse of anti-retroviral drugs, the study does
in the study from Southern and Eastern Africa. Theysuggest that aciclovir could be a useful extra weapon
enrolled 3,381 heterosexual volunteers, who werein the armoury of those fighting the epidemic.
infected with both Herpes and HIV. It is extremelyCurrently, the World Health Organisation recommends
common for patients with HIV to also have thethat anti-retroviral treatment begins when someone's
Type 2 Herpes virus.CD4 count falls below 350 per microlitre, rather than
Half of those taking part in the study werewait for the immune system to be even more
prescribed acyclovir, the anti-viral medication given tocompromised. Already, poor countries have difficulty
people with herpes, either whenever they experiencefunding therapy for patients, without having the pool
a breakout or as a daily treatment to suppress thefor those eligible increased.
virus. The others were given a placebo and bothThe discovery that the herpes treatment could stave
groups were followed for 24 months.off the point until anti-retroviral treatment is needed
The researchers were particularly eager to seecould not only ease health budgets but also allow
whether the CD4 cells in the patients fell, a keypatients to remain a little longer on less toxic
indicator of whether the virus was progressing. HIVmedication (the triple cocktail can have severe side
destroys the CD4 immune cells.effects).
It was discovered that the aciclovir reduced the risk